Figure 2

Differentially accumulated metabolites between three comparable groups. (A) Principal component analysis (PCA) of the variance-stabilized estimated raw counts of differentially accumulated metabolites. Bar plot showing numbers of DEMs in S2 vs S1 (B), S3 vs S2 (C), and S3 vs S1 (D) groups. The horizontal axis represents the differential expression multiple, and the vertical axis represents the degree of difference in metabolites meaning. The red dots indicated the upregulated expressed metabolites (Log2 FC ≥ 2), the blue dots indicated the downregulated expressed metabolites (Log2 FC ≤ 0.5).