Table 1 General characteristics of included patients based on D14 TSH levels.
Low (239) | High-normal (225) | High (135) | P | |
|---|---|---|---|---|
Age (years) mean (SD) | 31.52 (4.15) | 31.34 (4.57) | 30.40 (4.50) | 0.06 |
Endometrial thickness (mm) median (IQR) | 11.00 (3.00) | 11.00 (2.85) | 11.50 (3.00) | 0.10 |
AMH (pmol/L) median (IQR) | 17.98 (13.39) | 19.75 (13.39) | 21.1 (13.27) | 0.004 |
Infertility duration (years) median (IQR) | 3.00 (3.50) | 3.00 (3.00) | 3.00 (3.00) | 0.29 |
Basal TSH (mIU/L) mean (SD) | 1.86 (0.75) | 2.48 (0.76) | 2.89 (0.75) | < 0.001 |
FT4 (pmol/L) mean (SD) | 16.38 (2.19) | 16.25 (2.13) | 15.73 (2.03) | 0.02 |
FT3 (pmol/L) mean (SD) | 4.91 (0.61) | 4.89 (0.58) | 4.9 (0.59) | 0.94 |
LH (IU/L) mean (SD) | 5.56 (2.39) | 5.63 (2.4) | 5.86 (3.05) | 0.54 |
FSH (IU/L) mean (SD) | 6.91 (1.72) | 6.91 (2.05) | 6.8 (1.57) | 0.84 |
E2 on the HCG day (pmol/L) median (IQR) | 10,694.00 (6006.00) | 9884.00 (5736.50) | 11,795.00 (7532.00) | 0.004 |
Type of infertility n (%) | ||||
Primary | 106 (44.35%) | 107 (47.56%) | 67 (49.63%) | 0.59 |
Secondary | 133 (55.65%) | 118 (52.44%) | 68 (50.37%) | |
Causes of infertility n (%) | ||||
Male factors | 54 (22.59%) | 46 (20.44%) | 31 (22.96%) | 0.99 |
Ovulation dysfunction | 37 (15.48%) | 31 (13.78%) | 21 (15.56%) | |
Tubal and pelvic factors | 67 (28.03%) | 63 (28.00%) | 41 (30.37%) | |
Female mixed factors | 13 (5.43%) | 12 (5.33%) | 6 (4.44%) | |
Male and Female factors | 44 (18.41%) | 50 (22.22%) | 25 (18.52%) | |
Unexplained | 24 (10.04%) | 23 (10.22%) | 11 (8.15%) | |
Transferred embryos n (%) | ||||
Cleavage embryos | 160 (66.95%) | 160 (71.11%) | 71 (52.59%) | 0.001 |
Blastocyst | 79 (33.05%) | 65 (28.89%) | 64 (47.41%) | |
Blastocysts with good quality n (%) | ||||
0 | 19 (24.05%) | 12 (18.46%) | 6 (9.38%) | 0.07 |
1 | 60 (75.95%) | 53 (81.54%) | 58 (90.62%) | |
Cleavage embryos of good quality n (%) | ||||
0 | 21 (13.13%) | 18 (11.25%) | 0 (0%) | 0.003 |
1 | 68 (42.50%) | 57 (35.63%) | 23 (32.39%) | |
2 | 71 (44.37%) | 85 (53.12%) | 48 (67.61%) | |
β-HCG levels on the pregnancy day in women with clinical pregnancy median (IQR) | ||||
Cleavage embyros transfer | 616.50 (541.08) | 748.10 (557.60) | 928.80 (658.20) | 0.013 |
Blastocyst transfer | 1384.00 (1527.70) | 1228.00 (865.20) | 1541.50 (1044.75) | 0.10 |