Table 3 Placental oxidative stress biomarkers and apoptotic indices in G2 and G3.

From: RETRACTED ARTICLE: Exposure to pesticide components causes recurrent pregnancy loss by increasing placental oxidative stress and apoptosis: a case–control study

 

G2

(n = 26)

Abortions less than 3 times

G3

(n = 26)

Abortions more than 3 times

p-Value

NO. (µM/g wet weight placental tissues)

51.3 ± 18.9

56.3 ± 40.4

0.355

TBARS (µM/g wet weight placental tissues)

4.7 ± 0.7

5.8 ± 1.3

 < 0.001

GSH (µM/mg protein in placental tissue extract)

11.1 ± 2.8

7.1 ± 2.3

 < 0.001

SOD (U/mg protein in placental tissue extract)

4.8 ± 0.8

4.2 ± 0.8

0.007

Bcl-2 (ng/mg protein in placental tissue extract)

0.6 ± 0.2

0.4 ± 0.2

0.023

Caspase-3 (ng/ protein in placental tissue extract)

3.4 ± 0.5

3.8 ± 0.5

0.016

  1. One-way analysis of variance (ANOVA) was used for comparison.
  2. HCG, human chorionic gonadotropin; NO, placental nitric oxide; TBARS, thiobarbituric acid reactive substances; GSH, placental reduced glutathione; SOD, placental superoxide dismutase activity; Bcl-2, placental B-cell lymphoma 2; Caspase-3, placental cysteine-dependent aspartate specific protease-3.
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