Figure 2 | Scientific Reports

Figure 2

From: MTAP-ANRIL gene fusion promotes melanoma epithelial-mesenchymal transition-like process by activating the JNK and p38 signaling pathways

Figure 2

Overexpression of MTAP-ANRIL promoted metastasis and proliferation in vivo. (A) Representative hematoxylin and eosin (H&E) staining images of lung samples from mice injected with A875 melanoma cells. The black arrows indicate the lung metastatic tumors. (B) The number of metastatic nodules in the lungs of mice injected with A875 melanoma cells was analyzed. (C, D) Representative Ki67 staining images of tumors from mice injected with A875 melanoma cells. (E, F) The volume and weight of tumors in mice injected with A875 melanoma cells were calculated. The data are presented as the mean ± SD values. *P < 0.01.

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