Figure 4

Gene expression of ECM proteins after four days of treatment. Gene expression of type I (COL1A1) (A), III (COL3A1) (B), and type VI (COL6A3) (C) collagen and fibronectin (FN1) (D) in dermal fibroblasts. Gene expression of type I (COL1A1) (E), III (COL3A1) (F), and type VI (COL6A3) (G) collagen and fibronectin (FN1) (H) in pulmonary fibroblasts. The data are shown as the mean ± SD of triplicates (of triplicates of gene expression). The experiment was done on dermal and pulmonary donor one, and the data were analyzed by one-way ANOVA with Dunnett’s multiple comparisons test against the control. Asterisks indicate: not significant: ns p ≥ 0.05, * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.