Figure 2

Heat map of differentially expressed miRNAs (Top 25) with statistical significance (p < 0.05) which were increased in CIN2+ respect to ≤ CIN1, using differential expression analysis in DESeq2. The data correspond to the normalized counts to the Z-score (math transformation). Heatmaps were generated with normalized counts to the Z-score (math transformation) using the package ‘pheatmap’ using R version 1.0.12 (https://cran.r-project.org/web/packages/pheatmap/index.html).