Figure 4 | Scientific Reports

Figure 4

From: miRNAs signature as potential biomarkers for cervical precancerous lesions in human papillomavirus positive women

Figure 4

Interaction pathway between differentially expressed miRNAs and their respective inverse correlated mRNAs observed in the Ingenuity Pathway Analysis of proteins of pathways deregulated by HPV E6 and E7 oncoproteins. Twentysix target gene products with inverse correlation with 11 differentially expressed miRNAs were identified in the Ingenuity Pathway Analysis (QIAGEN Inc., https://digitalinsights.qiagen.com/IPA). Proteins of pathways deregulated by HPV E6 and E7 oncoproteins are from the KEGG Human Papillomavirus Infection (https://www.genome.jp/pathway/ko051659). The interactions between miRNAs and mRNAs was built using Cytoscape V3.7.1 (URL: https://cytoscape.org/).

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