Table 2 Multinomial logistics regression analysis of differences among the groups.

From: Association of systemic adverse reaction patterns with long-term dynamics of humoral and cellular immunity after coronavirus disease 2019 third vaccination

Ā 

Group 1 (nā€‰=ā€‰539)

Group 2 (nā€‰=ā€‰163)

Group 3 (nā€‰=ā€‰138)

Group 4 (nā€‰=ā€‰101)

Group 5 (nā€‰=ā€‰150)

Group 6 (nā€‰=ā€‰99)

Group 7 (nā€‰=ā€‰177)

Group 8 (nā€‰=ā€‰198)

Group 9 (nā€‰=ā€‰633)

Base

B (95% CI)

p-value

B (95% CI)

p-value

B (95% CI)

p-value

B (95% CI)

p-value

B (95% CI)

p-value

B (95% CI)

p-value

B (95% CI)

p-value

B (95% CI)

p-value

Female

Ā 

0.62 (0.18 to 1.07)

0.006

0.19 (āˆ’Ā 0.31 to 0.68)

0.45

0.79 (0.22 to 1.36)

0.007

0.57 (0.11 to 1.03)

0.016

0.20 (āˆ’Ā 0.36 to 0.76)

0.48

1.27 (0.81 to 1.74)

ā€‰<ā€‰0.001

0.93 (0.50 to 1.37)

ā€‰<ā€‰0.001

1.12 (0.77 to 1.47)

0.000

Age

Ā 

āˆ’Ā 0.04 (āˆ’Ā 0.06 to āˆ’Ā 0.03)

ā€‰<ā€‰0.001

āˆ’Ā 0.03 (āˆ’Ā 0.05 to āˆ’Ā 0.01)

0.001

āˆ’Ā 0.09 (āˆ’Ā 0.11 to āˆ’Ā 0.07)

ā€‰<ā€‰0.001

āˆ’Ā 0.06 (āˆ’Ā 0.07 to āˆ’Ā 0.04)

ā€‰<ā€‰0.001

āˆ’Ā 0.08 (āˆ’Ā 0.10 to āˆ’Ā 0.06)

ā€‰<ā€‰0.001

āˆ’Ā 0.09 (āˆ’Ā 0.11 to āˆ’Ā 0.08)

ā€‰<ā€‰0.001

āˆ’Ā 0.08 (āˆ’Ā 0.10 to āˆ’Ā 0.07)

ā€‰<ā€‰0.001

āˆ’Ā 0.12 (āˆ’Ā 0.13 to āˆ’Ā 0.10)

0.000

BMI

Ā 

āˆ’Ā 0.05 (āˆ’Ā 0.1 to 0.01)

0.104

āˆ’Ā 0.02 (āˆ’Ā 0.08 to 0.04)

0.47

āˆ’Ā 0.04 (āˆ’Ā 0.11 to 0.02)

0.21

āˆ’Ā 0.03 (āˆ’Ā 0.09 to 0.02)

0.24

āˆ’Ā 0.02 (āˆ’Ā 0.09 to 0.04)

0.49

āˆ’Ā 0.03 (āˆ’Ā 0.09 to 0.02)

0.22

āˆ’Ā 0.05 (āˆ’Ā 0.11 to 0.00)

0.044

āˆ’Ā 0.02 (āˆ’Ā 0.06 to 0.02)

0.26

Vaccine type (baseā€‰=ā€‰Pfizer)

Ā 

āˆ’Ā 0.7 (āˆ’Ā 1.17 to āˆ’Ā 0.23)

0.003

0.57 (0.13 to 1.01)

0.011

āˆ’Ā 0.75 (āˆ’Ā 1.41 to āˆ’Ā 0.09)

0.025

āˆ’Ā 0.06 (āˆ’Ā 0.5 to 0.38)

0.79

0.33 (āˆ’Ā 0.19 to 0.84)

0.22

āˆ’Ā 0.31 (āˆ’Ā 0.78 to 0.15)

0.189

0.01 (āˆ’Ā 0.41 to 0.42)

0.97

0.15 (āˆ’Ā 0.18 to 0.48)

0.38

Smoking

Ā 

āˆ’Ā 0.35 (āˆ’Ā 0.88 to 0.19)

0.20

āˆ’Ā 0.39 (āˆ’Ā 0.97 to 0.18)

0.181

āˆ’Ā 0.73 (āˆ’Ā 1.45 to 0.00)

0.052

āˆ’Ā 0.03 (āˆ’Ā 0.54 to 0.49)

0.92

āˆ’Ā 0.58 (āˆ’Ā 1.22 to 0.06)

0.078

āˆ’Ā 0.69 (āˆ’Ā 1.26 to āˆ’Ā 0.13)

0.033

āˆ’Ā 0.06 (āˆ’Ā 0.54 to 0.42)

0.80

āˆ’Ā 0.41 (āˆ’Ā 0.80 to āˆ’Ā 0.01)

0.044

Alcohol

Ā 

0.24 (āˆ’Ā 0.18 to 0.67)

0.26

0.44 (āˆ’Ā 0.04 to 0.91)

0.072

0.18 (āˆ’Ā 0.36 to 0.72)

0.52

0.13 (āˆ’Ā 0.31 to 0.57)

0.56

0.09 (āˆ’Ā 0.44 to 0.61)

0.74

0.46 (0.04 to 0.89)

0.033

0.22 (āˆ’Ā 0.19 to 0.63)

0.28

0.20 (āˆ’Ā 0.13 to 0.53)

0.24

Steroids

Ā 

āˆ’Ā 0.26 (āˆ’Ā 1.6 to 1.07)

0.70

āˆ’Ā 1.01 (āˆ’Ā 3.12 to 1.10)

0.35

āˆ’Ā 1.82 (āˆ’Ā 4.48 to 0.84)

0.180

āˆ’Ā 0.80 (āˆ’Ā 2.27 to 0.68)

0.29

āˆ’Ā 15.05 (āˆ’Ā 2566.91 to 2536.81)

0.99

āˆ’Ā 16.22 (āˆ’Ā 1713.08 to 1680.64)

0.99

āˆ’Ā 0.49 (āˆ’Ā 1.88 to 0.90)

0.49

āˆ’Ā 1.34 (āˆ’Ā 2.70 to 0.01)

0.053

Biologics

Ā 

āˆ’Ā 14.28 (āˆ’Ā 3545.89 to 3517.33)

0.99

0.80 (āˆ’Ā 1.59 to 3.19)

0.51

1.47 (āˆ’Ā 1.04 to 3.99)

0.25

0.17 (āˆ’Ā 2.3 to 2.65)

0.89

āˆ’Ā 13.94 (āˆ’Ā 4233.31 to 4205.42)

1.00

1.12 (āˆ’Ā 1.36 to 3.6)

0.26

0.91 (āˆ’Ā āˆ’Ā 1.09 to 2.90)

0.37

āˆ’Ā 0.39 (āˆ’Ā 2.86 to 2.09)

0.76

Hypertension

Ā 

āˆ’Ā 0.06 (āˆ’Ā 0.54 to 0.41)

0.79

āˆ’Ā 0.10 (āˆ’Ā 0.61 to 0.41)

0.69

āˆ’Ā 0.07 (āˆ’Ā 0.81 to 0.68)

0.86

0.05 (āˆ’Ā 0.46 to 0.56)

0.85

0.52 (āˆ’Ā 0.12 to 1.17)

0.11

0.00 (āˆ’Ā 0.57 to 0.57)

0.96

āˆ’Ā 0.09 (āˆ’Ā 0.60 to 0.43)

0.75

0.01 (āˆ’Ā 0.40 to 0.42)

0.97

Immunosuppression

Ā 

āˆ’Ā 14.77 (āˆ’Ā 2617.57 to 2588.02)

0.99

āˆ’Ā 14.71 (āˆ’Ā 3320.94 to 3291.52)

0.99

0.63 (āˆ’Ā 2.16 to 3.42)

0.66

0.53 (āˆ’Ā 1.34 to 2.39)

0.58

āˆ’Ā 13.60 (āˆ’Ā 3227.60 to 3200.39)

0.99

1.24 (āˆ’Ā 1.12 to 3.60)

0.30

0.11 (āˆ’Ā 1.9 to 2.11)

0.92

0.27 (āˆ’Ā 1.57 to 2.12)

0.77

Anticancer drugs

Ā 

0.6 (āˆ’Ā 1.79 to 2.99)

0.63

āˆ’Ā 18.29 (āˆ’Ā 25,723.2 to 25,686.61)

1.00

2.36 (0.33 to 4.40)

0.023

0.57 (āˆ’Ā 1.76 to 2.90)

0.63

āˆ’Ā 17.87 (āˆ’Ā 28,652.33 to 28,616.60)

1.00

1.23 (āˆ’Ā 1.28 to 3.74)

0.34

āˆ’Ā 18.36 (āˆ’Ā 25,998.17 to 25,961.45)

1.00

0.34 (āˆ’Ā 2.07 to 2.75)

0.78

Diabetes

Ā 

āˆ’Ā 0.07 (āˆ’Ā 0.78 to 0.65)

0.85

āˆ’Ā 0.17 (āˆ’Ā 0.89 to 0.55)

0.64

āˆ’Ā 0.05 (āˆ’Ā 1.19 to 1.09)

0.94

0.37 (āˆ’Ā 0.31 to 1.04)

0.29

0.48 (āˆ’Ā 0.35 to 1.31)

0.26

āˆ’Ā 0.63 (āˆ’Ā 1.73 to 0.47)

0.26

0.35 (āˆ’Ā 0.37 to 1.07)

0.40

āˆ’Ā 0.32 (āˆ’Ā 0.98 to 0.34)

0.34

Asthma

Ā 

0.23 (āˆ’Ā 0.96 to 1.43)

0.70

0.53 (āˆ’Ā 0.66 to 1.72)

0.38

1.02 (āˆ’Ā 0.23 to 2.27)

0.109

1.40 (0.47 to 2.33)

0.003

0.61 (āˆ’Ā 0.74 to 1.96)

0.37

1.16 (0.15 to 2.17)

0.024

0.58 (āˆ’Ā 0.50 to 1.66)

0.29

1 (0.15 to 1.86)

0.021

Dyslipidemia

Ā 

0.29 (āˆ’Ā 0.24 to 0.83)

0.29

0.45 (āˆ’Ā 0.11 to 1.01)

0.118

āˆ’Ā 0.16 (āˆ’Ā 1.08 to 0.77)

0.74

āˆ’Ā 0.27 (āˆ’Ā 0.93 to 0.39)

0.43

āˆ’Ā 0.05 (āˆ’Ā 0.84 to 0.74)

0.90

0.02 (āˆ’Ā 0.66 to 0.70)

0.95

0.08 (āˆ’Ā 0.53 to 0.69)

0.79

0.41 (āˆ’Ā 0.06 to 0.87)

0.086

  1. Significant values are in bold.
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