Table 3 Relationship between the groups and peak humoral or cellular immunity after the third vaccination.
| Ā | IgG(S) (Nā=ā2195) | Nab (Nā=ā2160) | T spot (Nā=ā1047) | |||
|---|---|---|---|---|---|---|
B (95% CI) | p-value | B (95% CI) | p-value | B (95% CI) | p-value | |
Female | ā 308.05 (ā 451.06 to ā 165.04) | ā<ā0.001 | ā 9.11 (ā 22.33 to 4.12) | 0.177 | ā 0.48 (ā 2.92 to 1.95) | 0.70 |
Age | ā 4.64 (ā 9.70 to 0.42) | 0.072 | ā 0.85 (ā 1.31 to ā 0.38) | ā<ā0.001 | ā 0.17 (ā 0.26 to ā 0.08) | ā<ā0.001 |
BMI | 38.94 (22.44 to 55.44) | ā<ā0.001 | 1.92 (0.40 to 3.45) | 0.013 | ā 0.07 (ā 0.34 to 0.2) | 0.60 |
Vaccine type (Moderna) | 1054.17 (914.52 to 1193.81) | ā<ā0.001 | 12.41 (ā 0.51 to 25.33) | 0.06 | 1.87 (ā 0.45 to 4.18) | 0.114 |
Group 1 | ||||||
Ā Group 2 | 140.95 (ā 121.13 to 403.04) | 0.29 | 21.89 (ā 2.34 to 46.11) | 0.077 | 2.52 (ā 1.88 to 6.92) | 0.26 |
Ā Group 3 | 194.46 (ā 94.93 to 483.86) | 0.188 | 37.36 (10.61 to 64.11) | 0.006 | 1.83 (ā 3.04 to 6.71) | 0.46 |
Ā Group 4 | 34.56 (ā 309.03 to 378.15) | 0.84 | 2.17 (ā 29.58 to 33.92) | 0.89 | 5.24 (ā 0.74 to 11.22) | 0.086 |
Ā Group 5 | 322.89 (47.89 to 597.88) | 0.021 | 29.32 (3.90 to 54.74) | 0.024 | 7.73 (3.26 to 12.21) | 0.001 |
Ā Group 6 | 833.86 (501.17 to 1166.54) | ā<ā0.001 | 36.52 (5.77 to 67.27) | 0.020 | 10.52 (4.40 to 16.64) | 0.001 |
Ā Group 7 | 374.92 (104.04 to 645.80) | 0.007 | 35.54 (10.5 to 60.58) | 0.005 | 8.00 (3.57 to 12.42) | ā<ā0.001 |
Ā Group 8 | 785.7 (529.73 to 1041.66) | ā<ā0.001 | 38.39 (14.67 to 62.11) | 0.002 | 15.19 (11.13 to 19.24) | ā<ā0.001 |
Ā Group 9 | 667.32 (461.01 to 873.62) | ā<ā0.001 | 37.04 (17.96 to 56.12) | ā<ā0.001 | 12.78 (9.31 to 16.25) | ā<ā0.001 |
Interval between second and third vaccination | ā 0.63 (ā 4.09 to 2.82) | 0.72 | ā 0.34 (ā 0.66 to ā 0.02) | 0.038 | 0.04 (ā 0.03 to 0.10) | 0.26 |
Smoking | ā 220.45 (ā 387.36 to ā 53.53) | 0.01 | ā 9.17 (ā 24.62 to 6.28) | 0.25 | ā 3.38 (ā 6.25 to ā 0.51) | 0.021 |
Alcohol | ā 86.54 (ā 220.38 to 47.29) | 0.21 | 1.82 (ā 10.56 to 14.20) | 0.77 | 1.79 (ā 0.48 to 4.06) | 0.123 |
Steroids | ā 77.61 (ā 615.21 to 459.99) | 0.78 | ā 82.92 (ā 132.59 to ā 33.25) | 0.001 | 4.66 (ā 3.16 to 12.48) | 0.24 |
Biologicals | ā 726.81 (ā 1608.64 to 155.02) | 0.106 | ā 139.8 (ā 221.28 to ā 58.32) | 0.001 | ā 6.07 (ā 20.72 to 8.59) | 0.42 |
NSAIDs | ā 17.76 (ā 279.73 to 244.20) | 0.89 | ā 41.96 (ā 66.26 to ā 17.67) | 0.001 | ā 0.10 (ā 4.38 to 4.18) | 0.96 |
Immunosuppression | ā 538.08 (ā 1300.90 to 224.74) | 0.167 | ā 79.86 (ā 150.34 to ā 9.38) | 0.026 | ā 11.74 (ā 23.17 to ā 0.31) | 0.044 |
Anticancer drugs | 171.09 (ā 730.55 to 1072.74) | 0.71 | ā 73.35 (ā 156.65 to 9.96) | 0.084 | ā 4.26 (ā 19.54 to 11.01) | 0.58 |
Hypertension | ā 103.81 (ā 275.6 to 67.99) | 0.24 | 1.31 (ā 14.58 to 17.19) | 0.87 | 0.59 (ā 2.19 to 3.37) | 0.68 |
Diabetes | ā 195.99 (ā 445.94 to 53.96) | 0.124 | ā 9.23 (ā 32.33 to 13.87) | 0.43 | ā 1.48 (ā 5.46 to 2.50) | 0.47 |
Asthma | ā 108.20 (ā 416.28 to 199.89) | 0.49 | ā 1.66 (ā 30.12 to 26.81) | 0.91 | ā 0.74 (ā 6.10 to 4.62) | 0.79 |
Dyslipidemia | 147.64 (ā 52.36 to 347.64) | 0.148 | 9.35 (ā 9.13 to 27.83) | 0.32 | 0.76 (ā 2.84 to 4.36) | 0.68 |
