Table 1 Demographic and clinical characteristics. The p-values for gender were obtained using chi-square tests for patients with migraines without aura group and the healthy controls. The p-values for age were obtained using Mann–Whitney U Tests for the MwoA patients and HCs. The p-values for the anxiety status were obtained using paired samples t-test for the pre- and post-taVNS patients. The p-values for the headache duration, headache attacks, headache intensity, depression status, and quality of life were obtained using Wilcoxon signed rank tests for the pre- and post-taVNS patients. SD standard deviation, MwoA migraine without aura, HCs healthy controls, taVNS transcutaneous auricular vagus nerve stimulation, post-taVNS after taVNS treatment, pre-taVNS before taVNS treatment; a, chi-square test; b, Mann–Whitney U Tests; c, Wilcoxon signed rank tests; d, paired samples t-test.

From: Altered functional brain network patterns in patients with migraine without aura after transcutaneous auricular vagus nerve stimulation

Characteristics

MwoA

HCs

p value

Gender (male/female)

10/25

14/24

0.45a

Age

31.97 ± 6.78

32.00 ± 11.16

0.16b

 

pre-taVNS

post-taVNS

 

Headache intensity (mean ± SD)

48.14 ± 17.13

27.71 ± 20.78

 

 < 0.001c

Anxiety status (mean ± SD)

39.55 ± 5.56

36.93 ± 6.39

 

0.002d

Depression status (mean ± SD)

41.54 ± 5.23

38.32 ± 5.58

 

 < 0.001c

Quality of life for migraine (mean ± SD)

60.40 ± 9.99

72.45 ± 8.89

 

 < 0.001c

Headache duration (h) (mean ± SD)

53.22 ± 49.19

30.91 ± 45.71

 

 < 0.001c

Headache attacks (mean ± SD)

3.89 ± 2.30

2.69 ± 2.31

 

0.009c