Table 5 XP G scores of the top hit compounds in the C-T network versus the highest enriched target genes.
| Â | RAC-alpha serine/threonine-protein kinase (3O96) | Caspase-3 (3DEI) | Tumor suppressor protein TP53 (2VUK) | Prostaglandin-endoperoxide synthase 2 (5F1A) | Endothelial nitric oxide synthase (1M9J) |
|---|---|---|---|---|---|
Luteolin | − 10.012 | − 6.543 | − 6.732 | − 7.534 | − 6.46 |
Apigenin | − 9.013 | − 6.245 | − 6.685 | − 6.811 | − 5.947 |
Allicin | − 3.335 | − 2.313 | − 3.105 | − 4.509 | 1.456 |
Diallyl trisulfide | − 1.607 | − 1.439 | − 1.535 | − 3.363 | 2.36 |
Silibinin | − 11.725 | − 8.855 | − 7.13 | – | – |
Piroxicam | − 3.664 | − 4.176 | − 0.956 | − 3.868 | 1.524 |
