Table 2 Comparative analysis of inflammatory mediators in liver tissue 6 h after brain death induction in different groups.

From: Immunomodulatory response in an experimental model of brain death

Cytokines

Groups

Control

BD

mRNA (relative expresión)

Protein (pg/mL)

mRNA (relative expresión)

Protein (pg/mL)

TNF-α

1.0 ± 0.1

17.9 ± 1.9

2.2 ± 0.1*

478.8 ± 109.5*

IL-1β

1.0 ± 0.2

17.3 ± 2.4

2.9 ± 0.2*

247.0 ± 29.8*

IL-6

1.0 ± 0.2

40.8 ± 4.8

2.7 ± 0.5*

590.5 ± 87.4*

IL-10

1.0 ± 0.4

13.2 ± 0.6

0.9 ± 0.4

17.6 ± 2.2

  1. BD brain death, TNF tumor necrosis factor.
  2. *p < 0.05 vs. Control. mRNA (TNF-α: *p = 0.0001; IL1-β: *p = 0.0001; IL-6: *p = 0.0001; IL-10: *p = 0.6248).
  3. Protein (TNF- α: *p = 0.0013; IL1- β: *p = 0.0001; IL-6: *p = 0.0001; IL-10: p = 0.0812).
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