Figure 1

Experimental salmon lice challenge of Coho salmon. (A) Naïve Okis were exposed to infective Lsal copepodites over two separate trials; CS1, where Okis were in full saltwater for ~ 24 h, or CS2, where Okis were in full saltwater for ~ 30 days. Coho salmon were sampled and fin with attached Lsal were preserved for RNA sequencing. (B) Coho salmon from both trials rapidly rejected Lsal, with > 95% of lice lost by 16 dpi. (C) Epithelial hyperplasia and granuloma formation were observed associated with the anterior portion of the lice by 4 dpi. By 10 dpi the lice were most often completely encapsulated. Except for 3 pre-adult mobile lice, there we no lice observed at 16 dpi.