Figure 1
From: Loss of SFXN1 mitigates lipotoxicity and predicts poor outcome in non-viral hepatocellular carcinoma
Identification of genes defining patient prognosis in non-viral HCC. (A) Screening analysis of the TCGA data for detecting genes downregulated and specifically associated with poor prognosis in non-viral HCC. Of 8,190 genes satisfying the criteria, 500 genes with the highest difference of P-values between the viral and non-viral HCC groups (ΔlogP = logPviral − logPnon-viral) are designated as “TOP500” genes. Details are described in the Methods and Results sections. (B) DAVID gene ontology analysis of the TOP500 genes. All of the 17 annotations with a FDR < 0.001 are shown. NS: not significant; FDR: false discovery rate.
