Table 1 Characteristics of control horses and horses with mild/moderate asthma (MMEA) and severe asthma (SEA) (mean ± SE).
Control (n = 15) | MMEA (n = 10) | SEA (n = 5) | p | |
|---|---|---|---|---|
Age (years) | 12 ± 1 | 16 ± 1 | 12 ± 1 | 0.051 |
Body weight (kg) | 524 ± 25 | 439 ± 43 | 517 ± 93 | 0.181 |
Sex | 0.103 | |||
Mare (n/%) | 3 (20%) | 0 (0%) | 2 (40%) | |
Stallion (n/%) | 0 (0%) | 2 (20%) | 0 (0%) | |
Gelding (n/%) | 12 (80%) | 8 (80%) | 3 (60%) | |
Mucus score (1–5) | 1.4 ± 0.19a | 2.6 ± 0.31b | 2.4 ± 0.93ab | 0.028 |
PaO2 (mmHg) | 102.0 ± 4.07 | 97.6 ± 3.52 | 87.2 ± 3.43 | 0.063 |
BALF | ||||
Neutrophils (%) | 1.9 ± 0.24a | 11.3 ± 1.47b | 39.1 ± 5.76b | < 0.001 |
Mast cells (%) | 1.8 ± 0.34 | 2.3 ± 0.57 | 1.0 ± 0.22 | 0.550 |
Eosinophils (%) | 0.1 ± 0.04 | 0.8 ± 0.40 | 0.2 ± 0.10 | 0.214 |
Lymphocytes (%) | 47.8 ± 2.06a | 55.4 ± 2.46b | 40.3 ± 5.81a | 0.041 |
Macrophages (%) | 48.2 ± 2.29b | 29.8 ± 2.65a | 19.0 ± 2.01a | < 0.001 |