Table 1 Clinical and hematological parameters in healthy dairy buffaloes treated with intravenous and intracervical suspension of AD-MSCs.

From: Allogenic adipose derived mesenchymal stem cells are effective than antibiotics in treating endometritis

Parametersa

Referenceb

Day0c

Day1

Day3

Day7c

Day15

p values

RR (bpm)

12–36

30.2 ± 0.2

29.8 ± 1.4

29.3 ± 1.3

29.5 ± 0.8

31 ± 1.5

0.2015

HR

40–80

54.2 ± 0.3

53.5 ± 1

53.6 ± 0.4

52.3 ± 0.7

54.5 ± 1.4

0.2541

RT (°C)

38–39

37.4 ± 0.5

37.7 ± 0.2

38.2 ± 0.3

38.4 ± 0.1

37.7 ± 0.2

0.2079

HEMOGLOBIN (g/dL)

8–15

11.2 ± 0.9

10.9 ± 0.1

11.1 ± 0.04

11 ± 0.1

11.2 ± 0.1

0.0599

PCV %

24–46

29.1 ± 0.1

29 ± 0.07

29.1 ± 0.1

29 ± 0.1

29.1 ± 0.1

0.0706

LEUKOCYTE (1 × 103/µL)

4–12

10.6 ± 0.1

10.5 ± 0.07

10.6 ± 0.09

10.6 ± 0.07

10.6 ± 0.07

0.215

ERYTHOCYTE (1 × 106/µL)

5–10

6.2 ± 0.05

6.07 ± 0.02

6.1 ± 0.02

6.1 ± 0.08

6.1 ± 0.06

0.9371

NEUTROPHIL (1 × 103/µL)

0.6–4

3.1 ± 0.1

3 ± 0.09

3.1 ± 0.09

3.3 ± 0.15

3.5 ± 0.2

0.1381

LYMPHOCYTES (1 × 103/µL)

2.5–7.5

5.4 ± 0.1

5.3 ± 0.09

5.4 ± 0.06

5.5 ± 0.1

5.6 ± 0.1

0.6576

MONOCYTES (1 × 103/µL)

0.025–0.84

0.08 ± 0.03

0.1 ± 0.06

0.1 ± 0.04

0.1 ± 0.05

0.8 ± 0.03

0.2301

EOSINOPHIL (1 × 103/µL)

0–2.4

1.3 ± 0.08

1.4 ± 0.06

1.45 ± 0.09

1.5 ± 0.05

1.2 ± 0.17

0.8021

BASOPHIL

 

0

0

0

0

0

0

ESR (mm/hr)

 

39.8 ± 1.2

42.1 ± 1.7

42.3 ± 1.7

41.6 ± 0.9

42.5 ± 1.1

0.3407

  1. aRR respiratory rate, HR heart rate, RT rectal temperature.
  2. bReference values were adopted from Smith, 202037.
  3. c2 × 107 cells were administered intravenously and intracervically on day-0 and day-7. Repeated measures one-way ANOVA (n = 6) with Tukey’s post hoc test was performed using GraphPad PRISM 8.