Figure 3 | Scientific Reports

Figure 3

From: Exogenous AMPA downregulates gamma-frequency network oscillation in CA3 of rat hippocampal slices

Figure 3The alternative text for this image may have been generated using AI.

Effect of IEM1460 and nifidepine on AMPA modulation of γ oscillation. (A) Example traces of field potentials recorded in hippocampal CA3 for CCH only, CCH + IEM1460 and CCH + IEM1460 + AMPA from a male SD rat. (B) Power spectra of the oscillatory activity for CCH alone (red line), CCH + IEM1460 (blue line) and CCH + IEM1460 + AMPA (green line) corresponding to the slice in (A). (C) Corresponding autocorrelograms of the oscillations displayed in (A). (D) The scatter plots of γ power for CCH only (red circles), CCH + IEM1460 (blue circles) and CCH + IEM1460 + AMPA (green circles), respectively. (E) The γ power normalized to CCH for CCH only, CCH + IEM1460 and CCH + IEM1460 + AMPA. (F) The peak frequency of oscillatory activity for CCH, CCH + IEM1460 and CCH + IEM1460 + AMPA. (G) The scatter plots of γ power for CCH (red circles), CCH + Nif (blue circles) and CCH + Nif + AMPA (green circles). (H) The normalized γ power for CCH only, CCH + Nif and CCH + Nif + AMPA. (I) The peak frequency of the oscillatory activity for CCH alone, CCH + Nif and CCH + Nif + AMPA.

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