Figure 6
From: Exogenous AMPA downregulates gamma-frequency network oscillation in CA3 of rat hippocampal slices
The effect of AMPA on fEPSP in CA3 area of hippocampal slices. (A) the schematic illustration about recording of synaptic transmission of CA3 from mossy fibers and recurrent collateral fibers, DG: dentate gyrus, recording electrode was placed at CA3(b) stratum pyramidale; the stimulus electrode was placed at either DG mossy fibers or CA3(c) stratum radiatum. (B) and (C) Example traces of fEPSP recorded in CA3 stratum pyramidale with stimulus at mossy fibers from dentate gyrus before (B) and after AMPA perfusion (C). (D) The fEPSP slope before and after AMPA perfusion with stimulation of mossy fibers. (E) and (F) Example traces of fEPSP recorded in CA3 stratum pyramidale with stimulus at CA3 stratum radiatum before (E) and after AMPA perfusion (F). (G) The fEPSP slope before and after AMPA perfusion with stimulation of recurrent collateral fibers.
