Figure 5

Infectivity of BCoV in solution after exposure to RF with high-applied power. Viral infectivity was assessed by CPE evaluation. Viral titers were determined upon titration on HRT-18G cells, as described in the methods, and evaluated at 6 days post inoculation. (A) Temperature profile from the cuvette exposures, measured by Opsens during the 15-min duration at higher applied power. (B) Virus titer (TCID₅₀/mL) following exposure to 8.4 GHz frequencies with low (6.3 W) or high (30.0 W) applied power for 15 min durations compared to a matched heating. (C) % Inactivation (i.e. data normalized to non-exposed virus sham) following exposure to specific GHz frequencies with low (6.3 W) or high (30.0 W) applied power for 15 min durations compared to a matched heating. Data are expressed as mean values ± S.E.M. of at least three independent experiments (n = 3). Statistically significant differences are noted by an asterisk, which represents p-value < 0.05.