Table 1 Median (IQR) values of echocardiographic parameters obtained during final echocardiographic examinations by A31P genotype.
Parameter | Genotype | P-value | |||||
|---|---|---|---|---|---|---|---|
HO (n = 23) | HT (n = 14) | WT (n = 7) | Overall | HO vs. HT | HO vs. WT | HT vs. WT | |
IVS diastole (cm) | 0.58 (0.48–0.62) | 0.51 (0.49–0.61) | 0.47 (0.35–0.53) | 0.047* | > 0.9999 | 0.04* | 0.25 |
IVS systole (cm) | 0.91 (0.77–0.98) | 0.84 (0.77–1.02) | 0.81 (0.65–0.95) | 0.34 | |||
LV diastole (cm) | 1.21 (1–1.38) | 1.29 (1.09–1.5) | 1.14 (1.07–0.32) | 0.29 | |||
LV systole (cm) | 0.46 (0.33–0.56) | 0.54 (0.42–0.73) | 0.51 (0.43–0.67) | 0.25 | |||
LVPW diastole (cm) | 0.57 (0.49–0.63) | 0.52 (0.49–0.56) | 0.46 (0.34–0.58) | 0.09 | |||
LVPW systole (cm) | 0.83 (0.77–1) | 0.86 (0.73–0.96) | 0.78 (0.58–0.88) | 0.43 | |||
FS (%) | 66.05 (57.–70.88) | 56.4 (51.2–65.4) | 52.4 (47.7–65.4) | 0.056 | |||
LA diastole (cm) | 1.29 (1.23–1.41) | 1.26 (1.15–1.39) | 1.16 (1.02–1.29) | 0.041* | > 0.9999 | 0.035* | 0.24 |
Ao systole (cm) | 0.84 (0.8–0.87) | 0.91 (0.85–0.97) | 0.93 (0.86–0.94) | 0.031* | 0.1 | 0.097 | > 0.9999 |
LA/Ao | 1.57 (1.52–1.61) | 1.42 (1.35–1.46) | 1.23 (1.22–1.25) | < 0.0001* | 0.0083* | < 0.0001* | 0.19 |
E Vmax (m/sec) | 0.68 (0.49–0.87) | 0.62 (0.56–0.69) | 0.62 (0.50–0.72) | 0.67 | |||
A Vmax (m/sec) | 0.79 (0.65–0.85) | 0.73 (0.61–0.82) | 0.78 (0.66–1.01) | 0.59 | |||
E/A (m/sec) | 0.74 (0.62–0.83) | 0.8 (0.69–1.17) | 0.63 (0.57–0.77) | 0.13 | |||
LAA flow (m/sec) | 42.8 (34.76–48.84) | 41.91 (37.39–48.3) | 48.97 (41.03–59.11) | 0.13 | |||
Septal bulge (mm) | 6.3 (6–7.2) | 6.15 (5.5–6.7) | 5.6 (5.4–6.33) | 0.1 | |||
Ao Vmax (m/sec) | 1.45 (0.98–2.24) | 1.82 (0.92–2.24) | 1.03 (0.75–3.28) | 0.73 | |||
P Vmax (m/sec) | 1.14 (0.96–1.37) | 0.97 (0.79–1.53) | 1.84 (0.74–2.22) | 0.35 | |||
