Table 3 Results of scoring systems used to test the healing effects of the tested materials on tibial bone defects with the different parameters.
Groups | New bone formation | Inflammatory response | Angiogenesis | Granulation tissue | Osteoblasts | Osteoclasts | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | |
Control | 3 0.11 | 25 0.89 | 0 0.0 | 0 0.0 | 0 0.0 | 0 0.0 | 24 0.86 | 4 0.14 | 0 0.0 | 1 0.04 | 3 0.11 | 24 0.86 | 0 0.0 | 0 0.0 | 4 0.14 | 24 0.86 | 0 0.0 | 20 0.71 | 0 0.0 | 8 0.29 | 28 0.100 | 0 0.0 | 0 0.0 | 0 0.0 |
ACTIVA | 0 0.0% | 28 0.100 | 0 0.0 | 0 0.0 | 0 0.0 | 28 0.100 | 0 0.0 | 0 0.0 | 0 0.0 | 5 0.18 | 23 0.82 | 0 0% | 26 0.93 | 2 0.07 | 0 0.0 | 0 0.0 | 0 0.0 | 26 0.93 | 0 0.0 | 2 0.07 | 2 0.07 | 26 0.93 | 0 0.0 | 0 0.0 |
MTA HP | 0 0.0 | 0 0.0 | 0 0.0 | 28 0.100 | 0 0.0 | 24 0.86 | 4 0.14 | 0 0.0 | 0 0.0 | 1 0.04 | 26 0.93 | 1 0.04 | 0 0.0 | 5 0.18 | 21 0.75 | 2 0.07 | 0 0.0 | 0 0.0 | 0 0.0 | 28 0.100 | 0 0.0 | 0 0.0 | 1 0.04 | 27 0.96 |
iRoot BP Plus | 0 0.0 | 0 0.0 | 0 0.0 | 28 0.100 | 0 0% | 26 0.93 | 2 0.07 | 0 0.0 | 0 0.0 | 4 0.14 | 24 0.86 | 0 0.0 | 0 0.0 | 9 0.32 | 18 0.64 | 1 0.04 | 0 0.0 | 0 0.0 | 0 0.0 | 28 0.100 | 0 0.0 | 0 0.0 | 2 0.07 | 26 0.93 |
