Table 4 Results of the mean rank, Kruskal–Wallis and Mann–Whitney U statistical tests for the scoring systems used to test the healing effects of the tested materials on tibial bone defects with the different parameters.
Parameter | Control | ACTIVA | MTA HP | iRoot BP Plus | P† |
|---|---|---|---|---|---|
New bone formation | 26.11 | 32.89 | 83.50 | 83.50 | 0.000 |
P1‡ = 0.026 | P1‡ = 0.000, P2‡ = 0.000 | P1‡ = 0.000, P2‡ = 0.000, P3‡ = 1.000 | |||
Inflammatory response | 95.93 | 39.50 | 47.21 | 43.36 | 0.000 |
P1‡ = 0.000 | P1‡ = 0.000, P2‡ = 0.040 | P1‡ = 0.000, P2‡ = 0.015, P3‡ = 0.392 | |||
Angiogenesis | 91.23 | 41.73 | 49.75 | 43.29 | 0.000 |
P1‡ = 0.000 | P1‡ = 0.000, P2‡ = 0.054 | P1‡ = 0.000, P2‡ = 0.018, P3‡ = 0.099 | |||
Granulation tissue | 94.00 | 15.00 | 61.23 | 55.77 | 0.000 |
P1‡ = 0.000 | P1‡ = 0.000, P2‡ = 0.000 | P1‡ = 0.000, P2‡ = 0.000, P3‡ = 0.196 | |||
Osteoblasts | 39.50 | 27.50 | 79.50 | 79.50 | 0.000 |
P1‡ = 0.038 | P1‡ = 0.000, P2‡ = 0.000 | P1‡ = 0.000, P2‡ = 0.000, P3‡ = 1.000 | |||
Osteoclasts | 15.50 | 41.50 | 85.00 | 84.00 | 0.000 |
P1‡ = 0.000 | P1‡ = 0.000, P2‡ = 0.000 | P1‡ = 0.000, P2‡ = 0.000, P3‡ = 0.556 |