Table 1 Demographic characteristics of the study participants.

From: Interaction between retinol intake and ISX rs5755368 polymorphism in colorectal cancer risk: a case–control study in a Korean population

Characteristics

Total (n = 2769)

Men (n = 1875)

Women (n = 894)

Control (n = 1846)

Case (n = 923)

p-valuea

Control (n = 1250)

Case (n = 625)

p-valuea

Control (n = 596)

Case (n = 298)

p-valuea

Age (years)

 Mean ± SD

56.1 ± 9.1

56.6 ± 9.7

0.200

56.6 ± 8.7

57.2 ± 9.4

0.205

54.9 ± 9.8

55.3 ± 10.2

0.643

 Missing

0 (0)

0 (0)

 

0 (0)

0 (0)

 

0 (0)

0 (0)

 

BMI (kg/m2, n, %)

 Mean ± SD

24.1 ± 2.7

23.6 ± 3.4

 < 0.001

24.4 ± 2.6

23.6 ± 3.1

 < 0.001

23.3 ± 2.8

23.7 ± 4.0

0.142

 < 25

1215 (65.8)

640 (69.3)

0.016

766 (61.3)

433 (69.3)

 < 0.001

449 (75.3)

207 (69.5)

0.064

 ≥ 25

620 (33.6)

283 (30.7)

476 (38.1)

192 (30.7)

144 (24.2)

91 (30.5)

 Missing

11 (0.6)

0 (0)

8 (0.4)

0 (0)

3 (0.5)

0 (0)

Educational status (n, %)

 Middle school or less

282 (15.3)

321 (34.8)

 < 0.001

175 (14.0)

183 (29.3)

 < 0.001

107 (17.9)

138 (46.3)

 < 0.001

 High school

587 (31.8)

369 (40.0)

329 (26.3)

266 (42.6)

258 (43.3)

103 (34.6)

 College or more

934 (50.6)

233 (25.2)

712 (57.0)

176 (28.2)

222 (37.3)

57 (19.1)

 Missing

43 (2.3)

311 (33.7)

34 (2.7)

0 (0)

9 (1.5)

0 (0)

Family history of colorectal cancer (n, %)

 No

1743 (94.4)

837 (90.7)

 < 0.001

1188 (95.0)

560 (89.6)

 < 0.001

555 (93.1)

277 (92.9)

0.926

 Yes

99 (5.4)

86 (9.3)

58 (4.6)

65 (10.4)

41 (6.9)

21 (7.1)

 Missing

4 (0.2)

0 (0)

4 (0.3)

0 (0)

0 (0)

0 (0)

Regular exercise (n, %)

 No

753 (40.8)

612 (66.3)

 < 0.001

489 (39.1)

387 (61.9)

 < 0.001

264 (44.3)

225 (75.5)

 < 0.001

 Yes

1047 (56.7)

311 (33.7)

716 (57.3)

238 (38.1)

331 (55.5)

73 (24.5)

 Missing

46 (2.5)

0

45 (3.6)

0

1 (0.2)

0

Smoking status (n, %)

 Non-smoker

818 (44.3)

409 (44.3)

0.156

247 (19.8)

145 (23.2)

0.082

571 (95.8)

264 (88.6)

 < 0.001

 Ex-smoker

687 (37.2)

318 (34.5)

671 (53.7)

303 (48.5)

16 (2.7)

15 (5.0)

 Current smoker

341 (18.5)

196 (21.2)

332 (26.6)

177 (28.3)

9 (1.5)

19 (6.4)

 Missing

0 (0)

 

0 (0)

0 (0)

0 (0)

0 (0)

Alcohol consumption (n, %)

 Non-drinker

560 (30.3)

279 (30.2)

 < 0.001

200 (16.0)

107 (17.1)

0.001

360 (60.4)

172 (57.7)

0.191

 Ex-drinker

169 (9.2)

129 (14.0)

136 (10.9)

103 (16.5)

33 (5.5)

26 (8.7)

 Current drinker

1117 (60.5)

515 (55.8)

914 (73.1)

415 (66.4)

203 (34.1)

100 (33.6)

 Missing

0

0

0

0

0

0

Marital status (n, %)

 Married

1654 (89.6)

773 (83.8)

 < 0.001

1161 (92.9)

557 (89.1)

 < 0.001

493 (82.7)

216 (72.5)

0.001

 Others

171 (9.3)

146 (15.8)

73 (5.8)

66 (10.6)

98 (16.4)

80 (26.9)

 Missing

21 (1.1)

4 (0.4)

16 (1.3)

2 (0.3)

5 (0.8)

2 (0.7)

Monthly average gross income (10,000 won/moth) (n, %)

 < 200

388 (21.0)

321 (34.8)

 < 0.001

254 (20.3)

222 (35.5)

 < 0.001

134 (22.5)

99 (33.2)

 < 0.001

 200–400

754 (40.9)

387 (41.9)

536 (42.9)

253 (40.5)

218 (36.6)

134 (45.0)

 > 400

545 (29.5)

215 (23.3)

362 (29.0)

150 (24.0)

183 (30.7)

65 (21.8)

 Missing

159 (8.6)

0 (0)

98 (7.8)

0 (0)

61 (10.2)

0 (0)

Occupation (n, %)

 Professional administrative, office jobs

481 (26.1)

189 (20.5)

 < 0.001

389 (31.1)

160 (25.6)

 < 0.001

92 (15.4)

29 (9.7)

 < 0.001

 Sale and service positions

403 (21.8)

38 (4.1)

308 (24.6)

28 (4.5)

95 (15.9)

10 (3.4)

 Agriculture, manufacturing, mining, army service

241 (13.1)

141 (15.3)

221 (17.7)

121 (19.4)

20 (3.4)

20 (6.7)

 Housekeeping, unemployment, and others

698 (37.8)

555 (60.1)

314 (25.1)

316 (50.6)

384 (64.4)

239 (80.2)

 Missing

23 (1.3)

0 (0)

18 (1.4)

0 (0)

5 (0.8)

0 (0)

Total energy intake (kcal/day)

1689.6 ± 560.4

2026.3 ± 534.0

 < 0.001

1730.4 ± 547.2

2127.4 ± 509.1

 < 0.001

1604.0 ± 578.4

1814.4 ± 523.5

 < 0.001

Retinol intakeb (µg/day)

78.7 ± 55.4

60.1 ± 39.5

 < 0.001

73.7 ± 49.2

55.9 ± 35.4

 < 0.001

89.2 ± 65.4

69.0 ± 45.8

 < 0.001

  1. Significance at p-value < 0.05.
  2. Significant values are in bold.
  3. ap-values were calculated using the Chi-square test for categorical variables and the t-test for continuous variables.
  4. bRetinol intake was adjusted for total energy intake using the residual method.