Table 2 Association between retinol intake and CRC risk.

From: Interaction between retinol intake and ISX rs5755368 polymorphism in colorectal cancer risk: a case–control study in a Korean population

Retinol intake (µg/day)

Controls

Cases

Model 1 [OR (95% CI)]

Model 2 [OR (95% CI)]

Total (n = 2769)

 T1 (< 48.75)

616 (33.4)

443 (48.0)

1.00

1.00

 T2 (48.75–88.17)

615 (33.3)

306 (33.2)

0.69 (0.58–0.83)

0.68 (0.54–0.86)

 T3 (> 88.17)

615 (33.3)

174 (18.9)

0.39 (0.32–0.48)

0.49 (0.37–0.63)

 p for trend

  

 < 0.001

 < 0.001

Men (n = 1875)

 T1 (< 47.20)

417 (33.4)

317 (50.7)

1.00

1.00

 T2 (47.20–83.41)

416 (33.3)

191 (30.6)

0.60 (0.48–0.76)

0.58 (0.43–0.77)

 T3 (> 83.41)

417 (33.4)

117 (18.7)

0.37 (0.29–0.48)

0.43 (0.31–0.60)

 p for trend

  

 < 0.001

 < 0.001

Women (n = 894)

 T1 (< 51.54)

198 (33.2)

124 (41.6)

1.00

1.00

 T2 (51.54–98.79)

199 (33.4)

116 (38.9)

0.93 (0.68–1.28)

1.14 (0.75–1.72)

 T3 (> 98.79)

199 (33.4)

58 (19.5)

0.47 (0.32–0.67)

0.73 (0.46–1.15)

 p for trend

  

 < 0.001

 < 0.001

  1. Model 1: crude model. Model 2: multivariate model, adjusted for age, sex, body mass index (BMI), family history of colorectal cancer, smoking status, alcohol consumption, regular exercise, education, occupation, monthly income, married status, and total energy intake.
  2. T tertile (µg/day).