Table 3 Association between ISX rs5755368 polymorphism and colorectal cancer risk.

From: Interaction between retinol intake and ISX rs5755368 polymorphism in colorectal cancer risk: a case–control study in a Korean population

ISX rs5755368

Controls

Cases

Model 1

Model 2

OR

95% CI

p-valuea

OR

95% CI

p-valuea

GG

22 (2.7)

27 (4.5)

1.00

  

1.00

  

AG

258 (31.5)

215 (35.8)

0.68

0.38–1.23

0.199

0.70

0.34–1.47

0.352

AA

539 (65.8)

358 (59.7)

0.54

0.30–0.97

0.038

0.55

0.27–1.14

0.108

Dominant

 AG + GG

280 (34.2)

242 (40.3)

1.00

  

1.00

  

 AA

539 (65.8)

358 (59.7)

0.77

0.62–0.96

0.018

0.76

0.58–0.99

0.045

Recessive

 GG

22 (2.7)

27 (4.5)

1.00

  

1.00

  

 AA + AG

797 (97.3)

573 (95.5)

0.59

0.33–1.04

0.067

0.60

0.29–1.24

0.168

  1. rs5755368 polymorphism A > G was available among 600 cases and 819 controls. Model 1: crude model. Model 2: multivariate model, adjusted for age, sex, body mass index (BMI), family history of colorectal cancer, smoking status, alcohol consumption, regular exercise, education, occupation, monthly income, married status, and total energy intake.
  2. ap-values were calculated using the Chi-square test.
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