Table 3 Factors associated with the lack of a response as determined in univariate and multivariate logistic regression models.
From: Booster effect of the third dose of SARS-CoV-2 mRNA vaccine in Japanese kidney transplant recipients
Variable | Univariate Odd ratio (95% CI) | P value | Multivariate Odd ratio (95% CI) | P value |
|---|---|---|---|---|
Age, year | 1.01 (0.97 to 1.06) | 0.52 | ||
Male gender | 0.77 (0.27 to 2.12) | 0.62 | ||
Body mass index, kg/m2 | 0.87 (0.74 to 1.02) | 0.08 | ||
Time post last transplantation, year | 0.90 (0.83 to 0.98) | 0.02 | 0.85 (0.75 to 0.96) | 0.01 |
Treatment with rituximab | 1.05 (0.35 to 3.15) | 0.93 | ||
Mycophenolic acid dose, mg/day∗ | 1.25 (1.06 to 1.46) | 0.006 | 1.27 (1.02 to 1.60) | 0.04 |
Tacrolimus | 0.84 (0.20 to 3.52) | 0.81 | ||
Hemoglobin, g/dL | 0.63 (0.46 to 0.86) | 0.004 | 0.51 (0.27 to 0.94) | 0.03 |
Lymphocyte, /μL | 0.997 (0.996 to 0.999) | < 0.001 | 0.997 (0.995 to 0.999) | 0.003 |
eGFR, mL/min/1.73m2 | 0.95 (0.92 to 0.98) | 0.003 | 0.96 (0.90 to 1.02) | 0.17 |
Ferritin, ng/mL | 1.00 (0.99 to 1.00) | 0.47 | ||
25(OH)D, ng/mL | 0.99 (0.92 to 1.05) | 0.67 | ||
Hypertension | 0.82 (0.28 to 2.38) | 0.72 | ||
Diabetes mellitus | 0.66 (0.19 to 2.26) | 0.51 | ||
Vaccine type, third | 2.66 (0.90 to 7.81) | 0.08 |