Figure 4 | Scientific Reports

Figure 4

From: Cross-reactivity trends when selecting scFv antibodies against snake toxins using a phage display-based cross-panning strategy

Figure 4

Titration DELFIAs. This figure shows examples of titration DELFIA graphs for three scFvs from each of the PLA2, LNTX, and SNTX campaigns. In Supplementary Fig. S2 the titration DELFIAs for all tested scFvs can be observed. Three control antigens, streptavidin and two of the antigens not used in the campaign for the discovery of the given scFv (i.e., antigens used in the SNTX campaign were used as control antigens in the PLA2 campaign, etc.), were included at the highest concentration (100 nM). In the following descriptions, (CP) and (NCP) refers to antibodies originating from cross-panned or non-cross-panned selectings respectively. (a) TPL0127_02_A02 (CP), (b) TPL_0067_02_E08 (NCP), (c) TPL0229_02_A03 (CP), (d) TPL0127_02_H06 (CP), (e) TPL0066_01_B08 (NCP), (f) TPL0230_02_F07 (CP), (g) TPL0127_01_F09 (CP), (h) TPL0065_02_E02 (CP), and (i) TPL0227_01_E01 (NCP).

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