Figure 2

Changes in intestinal morphology in pectin versus high fat diet in EAU. (a) Representative hematoxylin and eosin-stained ileum sections from C57Bl/6 J non-immunized (NI) mouse illustrating sample measurements of villus, crypt, submucosa, and muscularis (Top panel), as well as high fat and pectin-fed EAU mice at 1 or 2 weeks post-immunization (bottom panels). (b) Quantification of ileal measurements in fat vs. pectin diets. 1w: 1 week; 2w: 2 weeks (post-immunization); n = 6–18 animals/group; p < 0.05*, p < 0.001***; means are shown in the graph.