Table 5 Association between in-hospital mortality and baseline characteristics, procedural features, and hemorrhagic and thrombotic in-hospital complications.

From: Comparative effectiveness of Cangrelor in patients with acute coronary syndrome undergoing percutaneous coronary intervention: an observational investigation from the M.O.Ca. registry

 

Univariate logistic regression analysis

Multivariate logistic regression analysis

95% C.I

OR

p

95% C.I

OR

p

Age

1.036

1.099

1.067

 < 0.001

1.027

1.134

1.079

0.002

Female

1.108

3.840

2.063

0.022

0.228

1.422

0.569

0.227

STEMI

2.898

16.490

6.913

 < 0.001

2.476

44.302

10.473

0.001

Diabetes mellitus

1.049

3.569

1.935

0.035

0.760

5.618

2.066

0.155

Arterial hypertension

0.476

1.849

0.938

0.854

    

Dyslipidaemia

0.342

1.112

0.617

0.108

    

Smoking

0.176

0.832

0.383

0.015

0.127

1.242

0.398

0.113

Obesity

0.390

1.873

0.855

0.695

    

Prior PCI/coronary bypass

0.628

2.364

1.219

0.558

    

Prior AMI

0.579

2.472

1.197

0.627

    

Peripheral artery disease

0.129

2.323

0.547

0.413

    

History of bleeding

0.205

13.681

1.676

0.630

    

OAC use

0.460

3.175

1.208

0.701

    

CKD

1.962

6.528

3.579

 < 0.001

0.735

5.559

2.022

0.173

LVEF < 30%

2.543

10.075

5.061

 < 0.001

0.859

6.950

2.443

0.094

High-risk clinical profile

18.311

85.424

39.550

 < 0.001

9.264

70.566

25.568

 < 0.001

NIV

2.346

13.369

5.600

 < 0.001

0.221

3.082

0.825

0.774

Multivessel CAD

0.730

2.526

1.358

0.334

    

Complex PCI

1.486

5.213

2.784

0.001

0.655

4.841

1.781

0.258

Multivessel PCI

1.142

4.784

2.337

0.020

0.674

8.287

2.364

0.179

LM PCI

3.111

25.875

8.971

 < 0.001

0.154

5.002

0.878

0.884

Femoral access

7.127

25.804

13.561

 < 0.001

2.110

11.939

5.020

 < 0.001

Slow/no reflow

0.920

8.577

2.809

0.070

    

HBR-ARC

1.282

4.173

2.312

0.005

0.190

1.531

0.539

0.246

Cangrelor use

1.475

4.820

2.667

0.001

0.609

3.749

1.511

0.374

In-hospital bleedings

1.469

15.313

4.742

0.009

2.229

68.000

12.312

0.004

In-hospital ischemic complications*

0.840

7.711

2.545

0.099

    
  1. STEMI ST-elevation myocardial infarction, PCI Percutaneous coronary intervention, AMI Acute myocardial infarction, OAC Oral anticoagulation, CKD Chronic kidney disease, LVEF Left ventricular ejection fraction, NIV Non invasive ventilation, CAD Coronary artery disease, LM Left main, HBR-ARC High bleeding risk according to Academic Research Consortium.
  2. *Acute myocardial infarction, probable/definite ST, TIA/stroke.
  3. Significant values are in [bold].
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