Table 4 Magnitude of diurnal variation of RVD and hemodynamic parameters between healthy subjects and low-teens NTG.

From: Diurnal change of retinal vessel density related to hemodynamic variation in treatment-naïve low-teens normal-tension glaucoma

 

Healthy group (N = 32)

Low-teens NTG (N = 35)

P-value*

ΔMax.in peripapillary RVD (%)

Average

2.64 ± 1.55

3.85 ± 2.83

0.017

ONH

6.83 ± 3.90

10.43 ± 8.57

0.005

pSuperior

5.61 ± 3.29

9.85 ± 10.44

0.015

pInferior

7.03 ± 4.84

11.68 ± 9.67

0.008

pTemporal

6.72 ± 4.89

8.07 ± 4.38

0.216

pNasal

5.92 ± 3.92

8.90 ± 9.01

0.080

ΔMax.in macular RVD (%)

Average

3.38 ± 2.43

4.92 ± 3.83

0.036

Fovea

5.54 ± 7.22

4.44 ± 4.87

0.450

mSuperior

6.18 ± 4.30

7.13 ± 4.41

0.347

mInferior

7.35 ± 5.80

7.90 ± 4.78

0.658

mTemporal

5.59 ± 4.40

5.46 ± 5.49

0.910

mNasal

5.09 ± 3.93

8.38 ± 6.49

0.007

ΔMax.in hemodynamics (mmHg)

SBP

16.38 ± 7.90

20.43 ± 19.20

0.218

DBP

12.65 ± 7.17

16.90 ± 7.35

0.013

IOP

2.69 ± 1.46

2.71 ± 1.38

0.963

MOPP

7.14 ± 4.43

9.57 ± 5.27

0.025

  1. *Independent t-test, bolded values represent significance, P < 0.05.
  2. RVD = retinal vessel density; ONH = optic nerve head; SBP = systolic blood pressure; DBP = diastolic blood pressure; IOP = intraocular pressure; MOPP = mean ocular perfusion pressure.