Table 1 Entire values of drug solubility37.

From: Computational intelligence modeling of hyoscine drug solubility and solvent density in supercritical processing: gradient boosting, extra trees, and random forest models

Pressure (bar)

Temperature (K)

308 ± 0.1

318 ± 0.1

328 ± 0.1

338 ± 0.1

348 ± 0.1

ρscCO2 (kg m−3)

(y × 104)

ρscCO2 (kg m−3)

(y × 104)

ρscCO2 (kg m−3)

(y × 104)

ρscCO2 (kg m−3)

(y × 104)

ρscCO2 (kg m−3)

(y × 104)

170 ± 1

838.96

1.12 ± 0.017

776.53

1.13 ± 0.021

704.97

0.98 ± 0.033

625.09

0.84 ± 0.015

544.13

0.79 ± 0.015

200 ± 1

866.48

1.22 ± 0.022

813.52

1.34 ± 0.020

755.52

1.39 ± 0.038

692.68

1.34 ± 0.027

627.22

1.31 ± 0.025

230 ± 1

888.88

1.31 ± 0.024

841.89

1.45 ± 0.031

791.75

1.61 ± 0.044

738.63

1.67 ± 0.046

683.45

1.81 ± 0.061

260 ± 1

907.91

1.36 ± 0.027

865.12

1.55 ± 0.041

820.21

1.77 ± 0.062

773.36

1.89 ± 0.047

725.06

2.09 ± 0.058

290 ± 1

924.56

1.43 ± 0.030

884.91

1.6 ± 0.052

843.77

1.89 ± 0.054

801.33

2.11 ± 0.065

757.9

2.3 ± 0.064

320 ± 1

939.39

1.45 ± 0.022

902.22

1.68 ± 0.047

863.97

1.96 ± 0.070

824.82

2.12 ± 0.064

785.01

2.47 ± 0.054

350 ± 1

952.81

1.51 ± 0.025

917.65

1.72 ± 0.060

881.71

2.02 ± 0.040

845.13

2.26 ± 0.054

808.11

2.61 ± 0.071

380 ± 1

965.09

1.52 ± 0.038

931.61

1.78 ± 0.046

897.56

2.08 ± 0.075

863.05

2.34 ± 0.045

828.27

2.79 ± 0.075

410 ± 1

976.43

1.55 ± 0.035

944.38

1.79 ± 0.055

911.91

2.13 ± 0.066

879.12

2.44 ± 0.060

846.19

2.83 ± 0.094

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