Figure 5 | Scientific Reports

Figure 5

From: Establishment of a protocol to administer immunosuppressive drugs for iPS cell-derived cardiomyocyte patch transplantation in a rat myocardial infarction model

Figure 5

Evaluation of angiogenesis and arteriogenesis of the left ventricle in the peri-infarct myocardium 6 months after hiPSC-CM patch implantation. (A,B) Capillaries immunostained with anti-von Willebrand Factor (vWF) antibody to assess angiogenesis. Representative image of vWF staining (brown) (A) and the quantification of the number of vWF-positive cells (B). Scale bar 1000 μm. *P < 0.05, **P < 0.01. (C,D) Mature vessel immunostained with anti-vWF and α-smooth muscle actin (SMA) antibodies to assess arteriogenesis. Representative image of vWF (green) and αSMA (red) staining (C) and the quantification of the number of vWF and αSMA double-positive cells (D). Scale bar 100 μm. *P < 0.05, **P < 0.01.

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