Table 1 Demographic and baseline characteristics of participants, biochemical parameters and hormone and cyclophilin serum levels across one menstrual cycle. Variables with normal distribution presented as mean ± SEM and non-parametric variables shown as median and interquartile range (n = 11). Significant level set at *p < 0.05 and **p < 0.01. Statistical comparisons among phases were analysed by repeated measures ANOVA test for variables with normal distribution and Friedman test for non-parametric variables.
From: Cyclophilin B serum levels present variations across the menstrual cycle
Demographic characteristics | ||||
|---|---|---|---|---|
Age (years) | 29.0 ± 1.2 | |||
BMI (kg/m2) | 21.8 (20.3–22.6) | |||
Cyclophilin levels | Follicular phase | Periovulatory phase | Mid-luteal phase | P value |
CypB (pg/mL) | 429.0 (167.4–555.9) | 214.0 (32.9–421.0) | 239.9 (154.9–546.9) | 0.012* |
CypD (pg/mL) | 692.2 (9.0–836.3) | 581.3 (1.31–847.1) | 690.9 (13.6–803.9) | 0.097 |
Hormone levels | ||||
TSH (mU/L) | 3.3 ± 0.4 | 3.3 ± 0.4 | 3.5 ± 0.3 | 0.721 |
FT4 (ng/dL) | 1.2 ± 0.05 | 1.2 ± 0.05 | 1.2 ± 0.05 | 0.481 |
LH (U/L) | 5.2 (4.5–6.7) | 12.6 (6.4–26.9) | 3.8 (1.2–7.8) | 0.001** |
FSH (U/L) | 7.9 (7.0–8.6) | 8.6 (4.0–11.8) | 2.5 (2.2–5.7) | 0.007** |
Estradiol (pg/mL) | 47.8 (35.0–67.9) | 107.0 (80.8–293.0) | 138.7 (104.2–179.4) | 0.005** |
Prolactin (ng/mL) | 17.1 ± 1.5 | 15.9 ± 1.5 | 19.5 ± 3.2 | 0.503 |
Progesterone (ng/mL) | 0.6 (0.6–0.8) | 1.4 (0.9–3.0) | 8.9 (6.9–13.5) | 0.002** |
Hemogram and biochemical parameters | ||||
Haemoglobin (g/dL) | 13.7 ± 0.3 | 13.3 ± 0.3 | 13.5 ± 0.3 | 0.191 |
Leucocytes (number/µL) | 6165.4 ± 255.1 | 6736.2 ± 262.6 | 6390.9 ± 371.1 | 0.246 |
Neutrophils (number/µL) | 3500.0 ± 200.4 | 3936.0 ± 199.2 | 3445.5 ± 199.1 | 0.235 |
Lymphocytes (number/µL) | 1972.7 ± 131.4 | 2140.3 ± 139.2 | 2161.5 ± 212.9 | 0.293 |
Platelets (number/µL) | 231,076.9 ± 10,669.6 | 219,846.2 ± 10,066.35 | 221,461.5 ± 11,389.7 | 0.332 |
Glucose (mg/dL) | 87.5 ± 1.6 | 81.7 ± 2.0 | 84.9 ± 2.3 | 0.018* |
Total cholesterol (mg/dL) | 186.2 ± 8.1 | 183.8 ± 7.3 | 182.5 ± 8.9 | 0.767 |
HDL (mg/dL) | 75.6 ± 3.9 | 77.9 ± 3.4 | 76.3 ± 4.1 | 0.485 |
LDL (mg/dL) | 95.5 ± 6.1 | 91.2 ± 7.3 | 92.1 ± 7.8 | 0.471 |
TG (mg/dL) | 74.0 ± 5.5 | 66.1 ± 5.7 | 70.5 ± 5.1 | 0.237 |
