Figure 2

First pass analysis (FPA) acquisition protocol. A tissue attenuation curve (TAC) of an ROI placed inside pancreatic parenchyma and arterial input function (AIF) in the abdominal aorta. All 34 scans of a dynamic CT acquisition as used in MSM are represented by squared boxes on the curves. Two black colored boxes represent the two volume acquisitions required in FPA: the first scan is marked after crossing the threshold of 120 HU (tbase). For FPA1, the second scan is marked at the peak of the AIF (tmax). For FPA2, the second scan is taken ‘tp’ seconds after the first scan, as marked by triangles on the curve from t1–t10. D dispersion delay, tbase time of baseline acquisition of AIF, ti time taken for contrast injection, tmax time of peak acquisition of AIF, tp time at temporal center of the bolus.