Table 2 Mean ± SD blood flow (BF) values of carcinoma (ROI2) and parenchyma (ROI3) tissue for circular ROI using FPA1, FPA2 at all ten acquisition times and MSM.

From: Evaluation and timing optimization of CT perfusion first pass analysis in comparison to maximum slope model in pancreatic adenocarcinoma

Tissue type

FPA1

FPA2

MSM

tmax

t1

t2

t3

t4

t5

t6

t7

t8

t9

t10

Circular ROI blood flow (ml/100 ml/min) measurement

 Carcinoma

30.3 ± 19.2

36.7 ± 20.8

34.4 ± 17.6

32.8 ± 15.6

29.9 ± 17.3

29.8 ± 16.1

31.9 ± 20.0

27.3 ± 18.8

32.2 ± 21.0

37.9 ± 23.0

39.5 ± 26.6

42.0 ± 24.8

 Parenchyma

89.0 ± 31.7

105.4 ± 56.7

102.7 ± 56.1

99.6 ± 45.5

92.1 ± 32.1

91.4 ± 40.2

85.6 ± 37.5

89.6 ± 31.3

98.2 ± 36.8

102.0 ± 41.5

117.7 ± 44.5

106.8 ± 41.5

 T-test (p value)

 < 0.0001

0.0001

 < 0.0001

 < 0.0001

 < 0.0001

 < 0.0001

 < 0.0001

 < 0.0001

 < 0.0001

 < 0.0001

 < 0.0001

 < 0.0001

 Pearson’s correlation (r)

0.95

0.82

0.86

0.87

0.93*

0.94*

0.91*

0.93*

0.93*

0.92*

0.90

 
  1. Circular ROI were used to indicate the respective tissues with a high degree of confidence. Student’s t-test p value shows a significant difference between carcinoma and the parenchyma tissue. Correlation values marked with asterisk show the range of acquisition time (t4–t9) with the highest correlation (r > 0.90) between FPA2 and MSM.
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