Table 3 Association of mRNA expression of target genes with clinicopathological features in polyps.

From: Integrated bioinformatics and wet-lab analysis revealed cell adhesion prominent genes CDC42, TAGLN and GSN as prognostic biomarkers in colonic-polyp lesions

mRNA expression

Parameters

Size

Dysplasia

Location

Genes

RQ#

 < 10 mm

 ≥ 10 mm

P-value

High-grade

Low-grade

P- value

Proximal

Distal

P-value

CDC42

 < 1

66.7%

27.3%

0.17

11.1%

60.7%

0.010*

24.3%

66.7%

0.017*

 > 1

33.3%

72.7%

88.9%

39.3%

75.7%

33.3%

TAGLN

 < 1

55.6%

18.2%

0.16

11.1%

54.5%

0.03*

27.3%

44.4%

0.64

 > 1

44.4%

81.8%

88.9%

45.5%

72.7%

55.6%

GSN

 < 1

44.4%

36.4%

0.99

33.3%

45.5%

0.67

36.4%

44.4%

1.00

 > 1

55.6%

63.6%

66.7%

54.5%

63.6%

55.6%

  1. #Relative quantification, *Significant P-value.