Figure 1 | Scientific Reports

Figure 1

From: Plaque burden is associated with minimal intimal coverage following drug-eluting stent implantation in an adult familial hypercholesterolemia swine model

Figure 1

Histological verification of coronary atherosclerotic plaque type by OCT. Different types of plaques were selected by evaluation of OCT, which showed arteries without plaque (NP, a = e = h, green outline), with disease-free arcs (asterisk) and fibrous plaque (non-circumferential plaque) (IT/IX, b = f = i, blue outline) and with lipid-rich circumferential plaque (PIT/FCA, c = g = j, orange outline). The graph shows the distribution of plaque burden as evaluated by OCT (d). H&E (e–g) and ORO (h–j) staining of an artery without atherosclerotic plaque (e,h), with non-circumferential plaque (f,i) and with circumferential plaque (g,j). In ORO staining the lipids are stained in red (j); the asterisks indicate the plaque-free wall and the arrows indicate the lipid-rich regions. NP no plaque, IT/IX intimal thickening/intimal xanthoma, PIT/FCA pathological intimal thickening/fibrous cap atheroma.

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