Figure 1

(A) Hypothetical illustration on the distribution of 16 chromosomes (I-XVI) in the Rabl configuration in the yeast nuclei in the interphase 42,43,44. (B) Flow cytometry analysis for yeast cells cultured in the presence of raffinose. Inset is TEM images of the nuclei with the scale bar of 400 nm. (C) Schematic illustrations on the specimen preparation and XFEL-XDI experiments at SACLA 34,36,37,38,39.