Figure 6 | Scientific Reports

Figure 6

From: ARL-17477 is a dual inhibitor of NOS1 and the autophagic-lysosomal system that prevents tumor growth in vitro and in vivo

Figure 6

In vivo activity of ARL-17477. (A) Body weight changes of BALB/c mice (n = 3 mice per group) intravenously injected with vehicle (5% glucose) or ARL-17477 on days indicated by red arrows. (B) Tumor volume changes of MIA PaCa-2 xenograft mice (n = 7 mice per group) intravenously injected with vehicle or 10 mg/kg ARL-17477 on days indicated by red arrows. (C) Final tumor weight measured on day 27. Statistical comparisons were performed using unpaired Student’s t tests for two tailed p value. *p < 0.05, **p < 0.01.

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