Figure 4

Viral load and cytokine production between AB-ALI and PN-ALI CRpBECs grown at air liquid interface and infected with rhinovirus RV-A1. (A) Viral RNA was quantified over time using real-time quantitative PCR (RT-qPCR). A multiplex protein quantification assay (LEGENDPlex) was performed using apical supernatant to determine changes in (B) IFN-β, (C) IFN-λ1, and (D) IP-10. Data presented as mean ± SD. A color-matched symbol in both groups represents an individual donor. Data were analyzed using a Wilcoxon matched-pairs signed rank test. p < 0.05 was considered significant.