Figure 3

The 16-year follow-up Kaplan–Meier survival curves (Cox Proportional Hazards Model) for low versus high PAM concentration, using cutoffs of 93 ng/mL for incident atrial fibrillation (AF), (A) and incident heart failure (HF), (B) and 79.5 ng/mL for incident major adverse cardiovascular events (MACE), (C). n is the number of subjects (MPP sub-cohort with no history of cardiovascular disease), HR* for hazard ratio (fully adjusted Cox regression with respect to age, gender, BMI, systolic blood pressure, diastolic blood pressure, glucose, diabetes, LDL, HDL, total cholesterol, and triglycerides) and p-values for statistical significance.