Table 1 Patient and transplant characteristics NPM1mut AML.

From: Allogeneic hematopoietic stem cell transplantation and pre-transplant strategies in patients with NPM1-mutated acute myeloid leukemia: a single center experience

Characteristic

n

%

Number of patients

64

100

Median age (range), years

51 (32–70)

 

Gender

 Female

41

64

 Male

23

36

Karyotype

 Normal

53

83

 Abnormal

11

17

Molecular genetics

 FLT3-ITDhigh

23

36

 FLT3-ITDlow

6

9

 FLT3-TKD

5

9

Genetic risk according ELN 2017

 Favorable

37

58

 Intermediate

26

41

 Adverse

1

2

Transplant characteristics

 HLA-matching

  Matched related donor

14

22

  Matched unrelated

41

64

  Mismatched unrelated

9

14

 ATG

  Yes

48

75

  No

16

25

 Conditioning regimen

  Sequential FLAMSA based

22

34

  Other

42

67

  1. AML acute myeloid leukemia, alloHSCT allogeneic hematopoietic stem cell transplantation, FLAMSA fludarabine, amsacrine and high dose cytarabine based sequential conditioning regime.
Back to article page