Table 1 Product name, manufacturer, composition, active ingredients, RDA-values and age recommendation of the toothpastes according to the manufacturers’ information and enamel and dentin losses (µm, mean ± SD) in the different groups including control.

elmex Baby

CP GABA, Hamburg, Germany

Water, sorbitol, hydrated silica, hydroxyethyl cellulose, cocamidopropyl betaine, amine fluoride, flavoring, saccharine

500 ppm fluoride

70–80

0 to 2 years

37.0 ± 1.5^def

7.7 ± 1.9^g

elmex Kinder

1000 ppm fluoride

2 to 6 years

35.7 ± 2.3^ef

6.8 ± 2.3^g

elmex JUNIOR

1400 ppm fluoride

6 to 12 years

33.7 ± 1.5^f

11.3 ± 1.8^def

KINDER KAREX

Dr. Kurt Wolff, Bielefeld, Germany

Aqua, hydrated Silica, glycerin, hydrogenated starch hydrolysate, hydroxyapatite, xylitol, silica, cellulose gum, sodium methyl cocoyl taurate, sodium sulfate, 1,2‐hexanediol, caprylyl glycol, aroma, sodium cocoyl glycinate

Hydroxyapatite, xylitol

 < 50

From 0 years

37.9 ± 1.6^def

17.5 ± 2.2^ab

JUNIOR KAREX

Dr. Kurt Wolff, Bielefeld, Germany

Aqua, hydrated silica, glycerin, sorbitol, sodium methyl cocoyl taurate, sodium cocoyl glycinate, sodium hydroxide, xylitol, dicalcium phosphate dihydrate, calcium carbonate, 1,2-hexanediol, caprylyl glycol, silica, cellulose gum, sodium chloride, sodium saccharin, allantoin, aroma, limonene

Hydroxyapatite, xylitol, dicalcium phosphate dihydrate, calcium carbonate

n.a.

From 6 years

44.0 ± 1.5^abc

24.3 ± 5.3^a

nenedent Kinderzahncreme ohne Fluorid

Dentinox Gesellschaft für pharmazeutische Präparate Lenk & Schuppan, Berlin, Germany

Aqua, hydrated silica, glycerin, xylitol, propylene glycol, xanthan gum, aroma, sodium lauroyl sarcosinate, disodium EDTA, sodium chloride, CI 77891

13% xylitol

approx. 40

n.a.

41.0 ± 2.8^bcd

19.5 ± 3.6^a

nenedent Kinderzahn-creme homöopathie-verträglich mit Fluorid

Aqua, hydrated silica, glycerin, xylitol, propylene glycol, xanthan gum, aroma, sodium lauroyl sarcosinate, disodium EDTA, sodium fluoride, sodium chloride, CI 77891

500 ppm fluoride, 13% xylitol

n.a.

35.1 ± 1.8^ef

12.7 ± 2.3^cde

nenedent Kinderzahn-creme mit Fluorid

1000 ppm fluoride, 13% xylitol

n.a.

35.3 ± 1.9^ef

6.3 ± 2.1 ^g

nenedent Junior

1450 ppm fluoride, 13% xylitol

n.a.

6 to 12 years

35.0 ± 1.9^ef

8.2 ± 1.2 ^g

Putzi Kinderzahngel

DENTAL-Kosmetik, Dresden, Germany

Sorbitol, aqua, hydrated silica, xylitol, tetrapotassium pyrophosphate, xanthan gum, aroma, sodium C14-16 olefin sulfonate, calcium glycerophosphate, tocopheryl acetate, mica, CI 77891

Xylitol

40

0 to 3 years

44.3 ± 3.2^abc

20.3 ± 3.4^a

Putzi Calcium

Aqua, sorbitol, hydrated silica, propylene glycol, cellulose gum, tetrapotassium

pyrophosphate, sodium C14-16 olefin sulfonate, aroma, sodium fluoride, calcium glycerophosphate, sodium saccharin, sodium methylparaben, CI 77891

1000 ppm fluoride

35–40

Up to starting school

38.2 ± 2.3^def

13.7 ± 2.4^bcd

Putzi Erdbeere

Aqua, sorbitol, hydrated silica, propylene glycol, silica, aroma, cellulose gum, sodium fluoride, cocamidopropyl betaine, sodium saccharin, sodium methylparaben, CI 75470, CI 77891

1000 ppm fluoride

35–40

Up to starting school

36.7 ± 2.5^def

8.6 ± 2.5^efg

Sensodyne ProSchmelz Junior

GlaxoSmithKline, Munich, Germany

Aqua, sorbitol, hydrated silica, glycerin, PEG-6, cocamidopropyl betaine, xanthan gum, aroma, sodium fluoride, sodium saccharin, sucralose, titanium dioxide, sodium hydroxide, limonene

1450 ppm fluoride

35 \(\pm\) 15

6 years and older

35.8 ± 2.2^ef

7.9 ± 2.4 ^fg

Splat Baby

SPLAT, Frankfurt am Main, Germany

Hydrogenated starch hydrolysate, aqua, dicalcium phosphate dihydrate, hydrated silica, glycerin, calcium hydroxyapatite, xanthan gum, potassium thiocyanate, lactoferrin, lactoperoxidase, glucose oxidase, glucose pentaacetate, aloe barbadensis leaf extract, apple/banana extract, lonicera caprifolium flower extract, lonicera japonica flower extract, dipotassium glycyrrhizate, cocamidopropyl betaine, o-cymen-5-ol, glycyrrhiza glabra (licorice) root extract, vaccinium oxycoccos fruit extract, achillea millefolium extract, arginine

Calcium hydroxyapatite

n.a.

0 to 3 years

47.0 ± 2.2^a

23.9 ± 5.1^a

Splat Kids

Hydrogenated starch hydrolysate, aqua, glycerin, hydrated silica, calcium hydroxyapatite, cellulose gum, aroma, potassium thiocyanate, lactoferrin, lactoperoxidase, glucose oxidase, glucose pentaacetate, aloe barbadensis leaf extract, xanthan gum, cocamidopropyl betaine, lonicera caprifolium flower extract, lonicera japonica flower extract, glycyrrhiza glabra (licorice) root extract, vitis vinifera seed extract, sodium benzoate, potassium sorbate, arginine, lutein

Calcium hydroxyapatite

n.a.

2 to 6 years

45.6 ± 2.7^ab

22.4 ± 4.0^a

Splat Junior

Aqua, hydrogenated starch hydrolysate, hydrated silica, glycerin, calcium hydroxyapatite, xylitol, sodium coco-sulfate, gellulose gum, aroma, potassium thiocyanate, lactoferrin, lactoperoxidase, glucose oxidase, glucose pentaacetate, aloe barbadensis leaf extract, xanthan gum, magnolia officinalis bark extract, glycyrrhiza glabra root extract, caccinium macrocarpon fruit extract, juglans regia leaf extract, punica granatum seed extract, retinyl palmitate, tocopheryl acetate, sodium lauroyl sarcosinate, sodium benzoate, potassium sorbate, maltitol, citric acid, pentylene glycol, CI 77007, silica, sorbitol, capsanthin/capsorubin, CI 75470, helianthus annuus seed oil, mica, Cl 77891

Calcium hydroxyapatite, xylitol

n.a.

6 to 11 years

45.4 ± 3.5^ab

17.7 ± 3.5^abc

Weleda Kinder-Zahngel

Weleda, Schwäbisch Gmünd, Germany

Glycerin, water, silica, algin, calendula officinalis flower extract, prunus amygdalus dulcis oil, esculin, flavor, limonene

None

60

n.a.

45.0 ± 2.6^ab

22.4 ± 4.2^a

Control (erosion only)

39.8 ± 2.2^cde

20.1 ± 3.0^a