Figure 4

Morphological heterogeneity of microglial cells under various conditions as evidenced by convex hull parameters (different aspects of the convex polygons, with all interior angles < 180°, containing the whole cell shape). Various convex hull measurements (A–H) were performed in each group in terms of area (μm2) and distance (μm). Convex hull area (A), convex hull perimeter (B), mean radius of the convex hull (C), maximum span across the convex hull (D), diameter of the bounding circle (E), the ration max/min convex hull radii (F), convex hull circularity (G) and span ratio of the convex hull (H) were quantitatively analyzed.