Table 4 Multivariable analysis testing the association of liver graft estrogen receptor status with graft failure risk in female-to-male liver transplantation.

From: Abrogation of greater graft failure risk of female-to-male liver transplantation with donors older than 40 years or graft macrosteatosis greater than 5%

Variables

Female-to-male

Other combinations

Hazard ratio

p

Hazard ratio

p

 Positive graft estrogen receptor

5.54 (1.36–22.61)

0.017

0.76 (0.31–1.87)

0.543

 Donor age > 40 years

1.01 (0.97–1.06)

0.663

1.04 (1.00–1.08)

0.071

 Graft macrosteatosis > 5%

1.34 (0.42–4.23)

0.622

1.89 (0.75–4.80)

0.179

 Body mass index (kg/m2)

1.01 (0.84–1.22)

0.909

1.00 (0.99–1.01)

0.869

 Hepatocellular carcinoma

  Within the Milan criteria (vs. none)

0.39 (0.11–1.35)

0.137

1.15 (0.40–3.35)

0.796

  Beyond the Milan criteria (vs. none)

0.20 (0.04–1.13)

0.069

1.05 (0.27–4.01)

0.946

 Refractory ascites

0.07 (0.01–0.71)

0.024

1.07 (0.38–3.03)

0.897

 Preoperative continuous renal replacement

0.32 (0.01–9.45)

0.506

1.44 (0.27–7.62)

0.671

 Packed red blood cells (units)

1.14 (1.17–1.21)

 < 0.001

1.01 (1.06–1.14)

 < 0.001

  1. Multivariable analysis included the variables that were significant in the multivariable model in Table 3 while donor age and graft macrosteatosis are forced in to the model.
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