Table 4 Correlations* between postoperative complications and stage 3 AKI onset after aortic surgery.

From: The NephroCheck bedside system for detecting stage 3 acute kidney injury after open thoracoabdominal aortic repair

Patients

N = 45 (%)

Stage 3 AKI, n = 21

No stage 3 AKI, n = 24

p value [95% CI]

In-hospital mortality

11 (24.4)

9 (42.9)

2 (8.3)

0.006 [0.12–0.62]

Days to death

16 [3–58]

4.7 ± 6.4

5.7 ± 7

0.73 [− 0.47–0.35]

ICU stay

14 [6–34]

34 [10–51]

8 [6–16]

0.009 [0.1–0.61]

Hospital stay

32 [16–50]

37 [19–62]

21 [16–36]

0.12 [− 0.07–0.49]

Re-Thoracotomy

16(35)

13 (61,9)

3 (12,5)

< 0.001 [0.25–0.7]

Re-Laparotomy

4 (8.9)

2 (9.5)

2 (8.3)

0.89 [− 0.28–0.31]

Bleeding

    

Abdominal

3 (6.7)

3 (14.3)

0 (0)

0.057 [− 0.12–0.53]

Intracranial

4 (8.9)

3 (14.3)

1 (4.2)

0.24 [− 0.13–0.45]

pulmonary

7 (15.6)

7 (33.3)

0 (0)

< 0.001 [0.26–0.7]

Mass transfusion

26 (59.1)

18 (85.7)

8 (33.3)

< 0.001 [0.26–0.7]

packed red blood cells (bags)

11 [5–26]

26 [16–30]

7 [2–10]

< 0.001 [0.52–0.83]

platelet concentrate (bags)

4 ± 4.7

6.7 ± 5.6

1.7 ± 1.9

< 0.001 [0.27–0.71]

FFP (bags)

15 [.5–26]

26 [21–41]

2,5 [0–14.25]

< 0.001 [0.4–0.77]

Fibrinogen (g)

3 ± 3.6

4.9 ± 4.2

1.5 ± 2

0.001 [0.2–0.67]

Sepsis

9 (20)

9 (42.9)

0 (0)

< 0.001 [0.28–0.71]

MODS

8 (17.8)

8 (38.1)

0 (0)

< 0.001 [0.23–0.69]

Acute liver failure

7 (15.6)

7 (33.3)

0 (0)

0.02 [0.19–0.66]

AKI 1

7 (15.6)

   

AKI 2

3 (6.7)

   

AKI 3 /Dialysis

21 (44.9)

   

Time to AKI diagnosis (days)

1 [1, 2]

   

Invasive ventilation (h)

16 [9–560]

529 [130–1158]

10.5 [5.2–17.5]

< 0.001 [0.38–0.77]

Re-Intubation

8 (17.8)

4 (19)

4 (16.7)

0.84 [− 0.27–0.32]

Pneumonia

21 (46.7)

16 (76.2)

5 (20.8)

< 0.001 [0.31–0.73]

ARDS 1

3 (6.7)

1 (4.8)

2 (8.3)

0.64 [− 0.36–0.23]

ARDS 2

4 (8.9)

4 (19)

0 (0)

0.025 [0.04–0.57]

ARDS 3

11 (24.4)

10 (47.6)

1 (4.2)

< 0.001 [0.24–0.7]

Apoplexy

5 (11.1)

4 (19.0)

1 (4.2)

0.12 [− 0.06–0.49]

Spinal cord ischaemia

5 (11.1)

3 (14.3)

2 (8.3)

0.54 [− 0.21–0.38]

Vocal cord paresis

3 (6.7)

2 (9.5)

1 (4.2)

0.48 [− 0.19–0.39]

  1. AKI acute kidney injury, ICU intensive care unit, FFP fresh frozen plasma, MODS multi-organ dysfunction syndrome, ARDS acute respiratory distress syndrome.
  2. *Correlations were calculated with a univariable, logistic regression model and Firth’s bias correction.
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