Figure 3
From: High-LET radiation induces large amounts of rapidly-repaired sublethal damage
Sublethal damage repair curves for PC-3 (left) and U2OS (right) cells following exposure to two identical fractions separated by 15 min to 6 h (2 × 3 Gy X-rays or 2 × 0.75 Gy alpha particles, top) or mixed exposures (bottom, 3 Gy X-rays and 0.75 Gy alpha particles). X-ray exposed cells show clear recovery, while alpha-exposed cells show negligible effects. In contrast, repair is seen in mixed exposures of X-rays and alpha particles, regardless of the initial radiation, suggesting sublethal damage recovery occurs even following alpha exposures. Points are mean and standard deviation of measured survival (N = 3); solid lines are fits as described in the “Methods”.
