Figure 2

Correlations between serum leptin and % fMRI signal change for the MID gain versus no gain contrast between HC and MDD. Within MDD, higher leptin concentrations were associated with lower fMRI BOLD signal change for the MID gain versus no gain contrast in left insula and left dorsolateral putamen. Within HC, higher leptin concentrations were associated with higher fMRI BOLD signal change for the MID gain versus no gain contrast in left insula and left dorsolateral putamen.