Table 2 IOP reduction from the baseline between the SLT and latanoprost groups over time (mean ± SD, mmHg).

From: 24-Hour efficacy of single primary selective laser trabeculoplasty versus latanoprost eye drops for Naïve primary open-angle glaucoma and ocular hypertension patients

 

Eye

1 Week

4 Weeks

12 Weeks

P value

24-h mean IOP reduction

 SLT group

21

4.0 ± 2.8

2.4 ± 2.3^

3.2 ± 2.4

0.020†

 Latanoprost group

19

5.5 ± 2.7

5.1 ± 2.5

5.5 ± 2.0

0.088†

 P value

 

0.097*

0.001*

0.002*

0.005‡

Diurnal mean IOP reduction

 SLT group

21

3.8 ± 2.8

2.4 ± 3.1^

3.2 ± 3.0

0.017†

 Latanoprost group

19

5.2 ± 2.4

4.8 ± 2.6

4.9 ± 2.2#

0.360†

 P value

 

0.114*

0.016*

0.048*

0.032‡

Nocturnal mean IOP reduction

 SLT group

21

4.4 ± 3.2

2.4 ± 2.3^

3.2 ± 2.6

0.009†

 Latanoprost group

19

6.1 ± 3.6

5.9 ± 3.2

6.6 ± 2.8#

0.199†

 P value

 

0.115*

0.000*

0.000*

0.002‡

  1. IOP, intraocular pressure; SLT, selective laser trabeculoplasty; SD, standard deviation.
  2. *P value: statistical significance of the difference among SLT and latanoprost groups simultaneously.
  3. †P value: statistical significance of the difference between the time points at weeks 1, 4, and 12 within the same group.
  4. ‡P value: statistical significance of the crossover effect among 2 study groups and three measurement time points.
  5. ^Indicated a significant difference in mean IOP reduction between the time point and week 1 (P < 0.05).
  6. #Indicated a significant difference when compared diurnal mean IOP reduction with nocturnal mean IOP reduction in the latanoprost group (P < 0.05).
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