Table 3 The mean 24-h IOP, peak IOP, and 24-h IOP fluctuation at each time point across 12 weeks (mean ± SD, mmHg).

From: 24-Hour efficacy of single primary selective laser trabeculoplasty versus latanoprost eye drops for Naïve primary open-angle glaucoma and ocular hypertension patients

 

Eye

Baseline

1 Week

4 Weeks

12 Weeks

P value

24-Hour mean IOP

 SLT group

21

20.4 ± 4.3

16.4 ± 3.1#

18.0 ± 3.3#

17.8 ± 2.7#

< 0.001

 Latanoprost group

19

21.0 ± 4.5

15.6 ± 2.7#

15.9 ± 2.9#

15.5 ± 3.3#

< 0.001

 P value

 

0.668*

0.361*

0.043*

0.026*

0.003

Peak IOP

 SLT group

21

24.9 ± 5.2

19.0 ± 3.6#

21.5 ± 3.4#

21.1 ± 3.5#

< 0.001

 Latanoprost group

19

24.8 ± 5.0

18.3 ± 3.0#

19.2 ± 3.2#

18.3 ± 3.8#

< 0.001

 P value

 

0.912*

0.536*

0.037*

0.020*

< 0.001

24-Hour IOP fluctuation

 SLT group

21

8.3 ± 2.9

5.2 ± 1.5#

6.7 ± 2.4

7.0 ± 1.8

< 0.001

 Latanoprost group

19

7.4 ± 2.1

5.4 ± 2.2#

5.2 ± 1.5#

5.0 ± 2.2#

< 0.001

 P value

 

0.299*

0.804*

0.042*

0.004*

0.036

  1. IOP, intraocular pressure; SLT, selective laser trabeculoplasty; SD, standard deviation.
  2. *P value: statistical significance of the difference among SLT and latanoprost groups simultaneously.
  3. P value: statistical significance of the difference between the time points at baseline, weeks 1, 4, and 12 within the same group.
  4. P value: statistical significance of the crossover effect among 2 study groups and 4 measurement time points.
  5. #Indicated a significant difference between the time point and baseline IOP (P < 0.05).